VizHyal – Preservative Free Eye Drops – Sodium Hyaluronate 0.1% - for Treatment of Dry Eyes – 10ml

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Allergic type reactions such as rash, hives, itching, in rare cases possible swelling of the lips, eyes and mouth, shortness of breath, and more rarely wheezing Vizidor contains dorzolamide hydrochloride, a potent inhibitor of human carbonic anhydrase II. Following topical ocular administration, dorzolamide reduces elevated intra-ocular pressure, whether or not associated with glaucoma. Elevated intra-ocular pressure is a major risk factor in the pathogenesis of optic nerve damage and visual field loss. Dorzolamide does not cause pupillary constriction and reduces intra-ocular pressure without side effects such as night blindness or accommodative spasm. Dorzolamide has minimal or no effect on pulse rate or blood pressure. Uses the COMOD system. Patient must press the base of the bottle to release one measured dose. You can also prescribe the ComplEye aid which assists administration of the drops and prevents the tip touching the eye.

Unlike oral carbonic anhydrase inhibitors, topical administration of dorzolamide hydrochloride allows for the active substance to exert its effects directly in the eye at substantially lower doses and therefore with less systemic exposure. In clinical trials with dorzolamide, this resulted in a reduction in IOP without the acid-base disturbances or alterations in electrolytes characteristic of oral carbonic anhydrase inhibitors. Vizulize Intensive Dry Eye Drops are an ideal solution if you need more intensive symptom relief from dry eyes and the associated feelings of irritation, grittiness and discomfort. The advanced formulation features the highest level of the natural tear lubricant, Sodium Hyaluronate, in the Vizulize range to more intensively moisturise and hydrate.*The patient should instill one drop in the affected eye(s) as directed by the physician. The patient should blink a few times so that the drop spreads over their eye should be instructed to seek advice from their doctor, pharmacist or nurse if they are not sure how to administer their medicine. Composition: Hyaluronic acid sodium salt (high molecular weight), Hyaluronic acid sodium salt (low molecular weight) L-Glycine, Vitamin E, TPGS, Extract of Centella Asiatica (L.) Urban (titrated in asiaticoside 3%), Polyvinylpyrrolidone, D-Mannitol, Sodium phosphate monobasic monohydrate, Sodium Phosphate dibasic dodecahydrate, Sodium Chloride, water for injection. Hydroxypropyl guar or combination product containing trehalose can be used for more severe symptoms as they can reduce inflammation and protect ocular surface. For patients with moderate episodic or chronic discomfort with or without environmental stress. Episodic visual symptoms which are annoying and/or activity-limiting.

VIZcellose 1.0% is a sterile, ophthalmic solution that protects and moisturizes the ocular surface of the eye. VIZcellose 1.0% relieves the symptoms of dry eyes such as burning, itching and foreign body sensation. Acting as a lubricant, VIZcellose drops provide relief from dry eye conditions, including those associated with the use of PC, infrequent blinking, certain medical treatments, atmospheric pollution, dry atmospheres (e.g., air conditioning), and ophthalmic stress due to the use of eye lenses. VIZcellose 1.0% can be suggested in the case of mild dry eye syndrome, when immediate protective action and lasting relief is required. Hypersensitivity: signs and symptoms of local reactions (palpebral reactions) and systemic allergic reactions including angioedema, urticaria and pruritus, rash, shortness of breath, rarely bronchospasm Dorzolamide contains a sulphonamido group, which also occurs in sulphonamides and although administered topically, is absorbed systemically. Therefore the same types of adverse reactions that are attributable to sulphonamides may occur with topical administration, including severe reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis. If signs of serious reactions or hypersensitivity occur, discontinue the use of this preparation. Carmellose (CMC) is a polysaccharide, a biological polymer, known as mucilage. It increases the residence of tears on the eye surface, as well as increasing the viscosity of the tear film. The properties of carmellose protects the eye against irritation, and moisturizes the ocular surface, thus relieving the sensation of discomfort caused by dry eye by creating a protective, viscoelastic shield.

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Formulated to be naturally kind to eyes, Vizulize Intensive Dry Eye Drops are pH balanced to the eye’s tear fluid so as not to sting on application. Systane Balance (propylene glycol 0.6%) or Optive Plus (carboxymethylcellulose 0.5%, glycerine 1%, castor oil). 10ml, 6m expiry, contains preservative. Buffered solution with Calendula extract, Hamamelis extract, EDTA 0.12%, PHMB 0.0001%. Storage instructions Patients should also be instructed that ocular solutions, if handled improperly, can become contaminated by common bacteria known to cause ocular infections. Serious damage to the eye and subsequent loss of vision may result from using contaminated solutions. Recommend overnight treatment with a paraffin-based PF eye ointment: Xailin Night or Hylo-Night (formerly known as VitA-POS) or HydraMed Night Eye Ointments, 5g.

When dorzolamide was given orally to simulate the maximum systemic exposure after long-term topical ocular administration, steady state was reached within 13 weeks. At steady state, there was virtually no free active substance or metabolite in plasma; CA inhibition in RBCs was less than that anticipated to be necessary for a pharmacological effect on renal function or respiration. Similar pharmacokinetic results were observed after chronic, topical administration of dorzolamide. Put one drop in the affected eye(s) as directed by your doctor. Blink a few times so that the drop spreads over the eye. If you are not sure how to administer your medicine, ask your doctor, pharmacist or nurse.Hold the bottle directly below the cap and turn the cap to open the bottle. Do not touch anything with the tip of the bottle to avoid contamination of the solution.