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f Schematic illustration of CMH with an electrical stimulation and axonal neurofiliments regrow in vivo.
Then, two-terminal electrical resistance (Ω) was monitored using digital multimeter (Dawson), and the electrical conductivity was calculated as follows: Electrical conductivity (S cm −1) = L/ R × A, where R is (electrical resistance, Ω), A is (Atra of cross-sectional (cm 2) = 3. We found that axon numbers (NF200) increased in the peri-trauma area following injection of the MBs and CMHs, and an increase was observed in CMH + HFMF at 7 days postsurgery compared with the PBS group. These results also demonstrated that the electromagnetized GYBs promoted stem cell differentiation and neurite outgrowth. d Analysis of Iba-1, scar thickness and NF200-positive responses at peri-trauma areas ( n = 6, mean ± s.
This conductive microporous hydrogel (CMH), which is composed of positively charged GYBs (electromagnetized generators) and negatively charged microbeads (MBs, interconnected pore formation and pore size control in the brain cavity), can be reshaped and reassembled by shear-thinning force, facilitating the construction of a three-dimensional porous scaffold (Fig. The BOLD activation maps were created using the 3dDeconvolve general linear model function with the given boxcar design of the stimulation paradigm by AFNI 56.
respectively, indicating a negligible difference in the NF200-positive area between the two groups (Fig. During the late phase of recovery from TBI, residual neural circuits were reconstructed, perhaps partially compensating for the lost parenchyma function 45. f), resulting from the promotion of neuroplasticity to produce a significant functional recovery of the corticostriatal and corticolimbic tracts. The NSC cells were isolated from ED 14−15 Wistar rat embryos using a previously described protocol with modification 49.
Electromagnetized gold nanoparticles mediate direct lineage reprogramming into induced dopamine neurons in vivo for Parkinson’s disease therapy. To understand the penetration depth of HFMF, the eddy current on cys-GYBs induced by HFMF was performed on a 10 cm of fluorine-doped tin oxide (FTO) substrate (Supplementary Fig. The fractional coverages of cys-GYB on the surface of microbeads were quantified by Imaris software.