PICO Neo3 Link 2-in-1 Virtual Reality Headset

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What is the accuracy of clinical prediction models and tools (clinical history, cardiovascular risk factors, physical examination) in evaluating stable chest pain of suspected cardiac origin?

Population: Which population are we interested in? How best can it be described? Are there subgroups that need to be considered? The Pico Neo 3 Pro is equipped with a 4K LCD display that provides a resolution of 3664 x 1920 pixels. The display’s resolution has been slightly reduced compared to its predecessor. While the Pico Neo 2 still displayed 1960 x 2160 pixels per eye, the Neo 3 has a resolution of 1832 x 1920. However, the Neo 3 Pro still provides a better viewing experience due to the improved refresh rate of 90 Hz and its 98° field of view. These two upgrades significantly improve the immersive VR experiences of the Pico Neo 3. When designing review questions and protocols, it is important to consider possible intercurrent events (events that occur after starting treatment and either preclude the observation of the variable, or affect its interpretation, such as death, non-adherence to treatment or stopping treatment) and how these will be dealt with in any analysis in the guideline, if different identified studies analyse the data in different ways. Clinical trials are increasingly following the Estimand framework (European Medicines Agency), which attempts to increase the clarity of the precise treatment effect that an individual study is estimating.Examples of review questions that include analysis targeting complex interventions are shown in box 4.3. An understanding of the expected mechanisms by which outcomes occur can help guide which interventions are most worthwhile to study in particular settings or questions. Comparator or reference standard: The test with which the index test is being compared, usually the reference standard (the test that is considered to be the best available method for identifying the presence or absence of the condition of interest – this may not be the one that is routinely used in practice). At the start of guideline development, the key issues and draft questions listed in the scope should be translated into review questions and review protocols.

What is the effectiveness of surgeon seniority (consultant or equivalent) in reducing the incidence of mortality, the number of people requiring reoperation, and poor outcome in terms of mobility, length of stay, wound infection and dislocation? If using McAfee, Norton, or any other anti-virus, try disabling them or adding an exception for Virtual Desktop Streamer Steyerberg EW, Bleeker SE, Moll HA et al. (2003) Internal and external validation of predictive models: A simulation study of bias and precision in small samples. Journal of Clinical Epidemiology 56: 441–7 It doesn’t just have more raw power, the Pico 4 has a higher resolution display too, with its single 4,320 x 2,160 pixel screen that provides 2,160 x 2,160 per eye ( up from the Quest 2’s 1,832 x 1,920 pixels). It also provides players with a wider field of view at 105 degrees, meaning you can see more of the virtual world by moving your eyes rather than having to turn your whole head.In people with localised or locally advanced prostate cancer, which risk stratification models, tools and categorising systems perform better in indicating risk of poor outcomes? Craig P, Cooper C, Gunnell D et al. on behalf of the MRC (2011) Using natural experiments to evaluate population health interventions: new Medical Research Council guidance. London: Medical Research Council

Adapting recommendations from previously published guidelines, either other NICE guidelines or guidelines from other organisations that are assessed to be sufficiently high quality using the AGREE II instrument. Comparators: What are the alternatives to the intervention being examined (for example, other interventions, usual care, placebo)? Population: To which populations would the test be applicable? How can they be best described? Are there subgroups that need to be considered? The review questions should cover all key areas specified in the scope but should not introduce new areas. They should build on the draft questions in the scope and usually contain more detail. For details on developing the scope, see the chapter on the scope. In people with suspected hypertension, which test is most accurate in identifying whether hypertension is present, as indicated by the reference standard of ambulatory blood pressure measurement?preferences of people using services, family members or carers or the public for different treatment or service options, including the option of foregoing treatment or care Skivington K, Matthews L, Simpson S et al. (2021a) Framework for the development and evaluation of complex interventions: gap analysis, workshop and consultation-informed update. Health Technol Assess 25:57 Altman DG, Vergouwe Y, Royston P et al. (2009) Prognosis and prognostic research: validating a prognostic model. BMJ 338: b605