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UTIs are among the most common bacterial infections in the United States. They are especially prevalent in females, with 2022 research showing that 40% of females will have one during their lifetimes. UTIs also tend to reoccur. Greenblatt DJ, von Moltke LL, Perloff ES, et al. Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin Pharmacol Ther 2006;79:125-33. View abstract. However, research on the benefits of probiotics is ongoing. What are the signs you need probiotics?
Are Cranberry Pills Good for You? Benefits, Side Effects and
Juthani-Mehta M, Van Ness PH, Bianco L, et al. Effect of cranberry capsules on bacteriuria plus pyuria among older women in nursing homes: a randomized clinical trial. JAMA. 2016;316(18):1879-87. View abstract. Cranberry juice is one of the most well-established natural treatments for UTIs. People also use it to clear other infections and speed wound recovery. Most UTIs develop when bacteria enter the urinary tract from outside the body. The species most likely to cause UTIs include: Singh I, Gautam LK, Kaur IR. Effect of oral cranberry extract (standardized proanthocyanidin-A) in patients with recurrent UTI by pathogenic E. coli: a randomized placebo-controlled clinical research study. Int Urol Nephrol 2016;48(9):1379-86. View abstract. Ohnishi, R., Ito, H., Kasajima, N., Kaneda, M., Kariyama, R., Kumon, H., Hatano, T., and Yoshida, T. Urinary excretion of anthocyanins in humans after cranberry juice ingestion. Biosci.Biotechnol.Biochem 2006;70(7):1681-1687. View abstract.Some sexual intercourse can introduce bacteria and other microbes into the urinary tract. Practicing good sexual hygiene can help to reduce this risk. Bianco, L., Perrelli, E., Towle, V., Van Ness, P. H., and Juthani-Mehta, M. Pilot randomized controlled dosing study of cranberry capsules for reduction of bacteriuria plus pyuria in female nursing home residents. J Am.Geriatr Soc 2012;60(6):1180-1181. View abstract.
Probiotics as Prophylaxis for Urinary Tract Efficacy of Probiotics as Prophylaxis for Urinary Tract
Jepson RG, Williams G, Craig JC. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 2012 17;10:CD001321. View abstract. Reid, G., Hsiehl, J., Potter, P., Mighton, J., Lam, D., Warren, D., and Stephenson, J. Cranberry juice consumption may reduce biofilms on uroepithelial cells: pilot study in spinal cord injured patients. Spinal Cord. 2001;39(1):26-30. View abstract. Study author Dr Ashton Harper, medical director at ADM Pro Chambers BK, Camire ME. Can cranberry supplementation benefit adults with type 2 diabetes? Diabetes Care 2003;26:2695-6. View abstract.
Bodel P, Cotran R, and Kass E. Cranberry juice and the antibacterial action of hippuric acid. J.Lab & Clin.Med. 1959;54(6):881-888. The urogenital tract comprises both the urinary tract and the vagina and both contain a microbiome (bacteria) in the same way as the gastrointestinal tract. Lactobacillus is the primary bacteria of the vagina of healthy women and the growth of too many other strains can lead to an imbalance in the natural bacteria of the vagina. Howell, A. B. and Foxman, B. Cranberry juice and adhesion of antibiotic-resistant uropathogens. JAMA 6-19-2002;287(23):3082-3083. View abstract. Avorn J, Monane M, Gurwitz J, Glynn R I, Choodnovskiy I, and Lipsitz L A. Reduction of bacteriuria and pyuria using cranberry juice. JAMA 1994;272(8):588-590. It is much more important for an individual to support their overall health by focusing on diet and lifestyle as a whole rather than on taking one specific supplement.
cranberry and probiotics in intestinal and The role of cranberry and probiotics in intestinal and
research into the effectiveness of cranberries for UTIs has found it to be effective. However, its effectiveness may vary from person to person, and more research is needed regarding which type of cranberry product and which dose is most effective. According to limited research, taking other supplements alongside vitamin C may maximize its benefits.
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Ruel, G., Pomerleau, S., Couture, P., Lemieux, S., Lamarche, B., and Couillard, C. Favourable impact of low-calorie cranberry juice consumption on plasma HDL-cholesterol concentrations in men. Br J Nutr 2006;96(2):357-364. View abstract. Takahashi S, Hamasuna R, Yasuda M, Arakawa S, Tanaka K, Ishikawa K, Kiyota H, Hayami H, Yamamoto S, Kubo T, Matsumoto T. A randomized clinical trial to evaluate the preventive effect ofcranberry juice (UR65) for patients with recurrent urinary tract infection. J Infect Chemother 2013;19(1):112-7. View abstract. Jepson RG, Craig JC. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 2008;(1):CD001321. View abstract. Some brands add vitamin C and other micronutrients to further enrich their products and help protect your overall health and well-being.( 4) What to Look for in Cranberry Supplements