Terumo Syringe 2.5ml Luer Lock Syringe, Pack of 100

Product Information

Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. The Hamilton 1000 series syringes offer a mid-volume Gastight syringe solution with an ideal capacity for dispensing volumes ranging from 100 µL to 100 mL. This syringe series boasts a variety of termination and needle options, providing exceptional versatility and adaptability. The full amount of solution should be inserted slowly into the space between the gum and the cheek (buccal cavity).

Midazolam may be used during pregnancy if clearly necessary. The risk for new-born infants should be taken into account in the event of administration of midazolam in the third trimester of pregnancy. Overdose of benzodiazepines is usually manifested by degrees of central nervous system depression ranging from drowsiness to coma. In mild cases, symptoms include drowsiness, mental confusion and lethargy, in more serious cases, symptoms may include ataxia, hypotonia, hypotension, respiratory depression, rarely coma and very rarely death. In case of co-administration of metaraminol and ergot alkaloids, there is a risk of vasoconstriction and/or hypertensive crisis. Co-administration with protease inhibitors (e.g. Saquinavir and other HIV protease inhibitors) may cause a large increase in the concentration of midazolam. Upon co-administration with ritonavir-boosted lopinavir, the plasma concentrations of intravenous midazolam increased by 5.4-fold, associated with a similar increase in terminal half-life. Always dispose of used needles properly. Don’t dispose of needles in the regular trash. Visit SafeNeedleDisposal.org to learn more.Nevertheless, if you are so inclined to convert between units of insulin and milligrams, you can use this handy conversion tool: Insulin: Units To Milligrams (mg) Tool St John's Wort decreased plasma concentrations of midazolam by about 20-40% associated with a decrease in terminal half-life of about 15-17%. Depending on the specific St John's Wort extract, the CYP3A4-inducing effect may vary. Published clinical studies show that oromucosal midazolam was administered to approx 443 children with seizures. Respiratory depression occurs at a rate of up to 5%, although this is a known complication of convulsive seizures as well as being related to midazolam use. One episode of pruritus was possibly attributed to the use of buccal midazolam.

Co-administration with midazolam may cause enhanced sedation or respiratory and cardiovascular depression. Palpitations; sinus or ventricular tachycardia; bradycardia; other cardiac arrhythmias (especially in patients with myocardial infarction); fatal ventricular arrhythmia reported in Laennec's cirrhosis

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A second or repeat dose when seizures re-occur after an initial response should not be given without prior medical advice (see section 5.2).