Calprofen Ibuprofen Suspension Sachets, Sugar & Colour Free, Pain & Fever Relief for 3+ Months, Strawberry Flavour, 5 ml, 12-Count

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Clinical studies suggest that use of ibuprofen, particularly at a high dose (2400 mg/day) may be associated with a small increased risk of arterial thrombotic events such as myocardial infarction or stroke. Overall, epidemiological studies do not suggest that low dose ibuprofen (e.g. < 1200mg/day) is associated with an increased risk of arterial thrombotic events. The lowest effective dose should be used for the shortest duration necessary to relieve symptoms (see section 4.4). If you’re looking for pain relief for your children, Nurofen for children comes in liquid form or chewable capsules for managing colds and flu symptoms, fever, and teething pain. The products aim to provide your child with up to 8 hours relief.

Ibuprofen should be used with caution in patients suffering from, or with a previous history of, bronchial asthma, chronic rhinitis or allergic disease, since such patients may have NSAID – sensitive asthma which has been associated with severe bronchospasm, urticaria or angioedema. with voriconazole and fluconazole (CYP2C9 inhibitors), an increased S (+)-ibuprofen exposure by approximately 80 to 100% has been shown. Reduction of the ibuprofen Dyspepsia, diarrhoea, nausea, vomiting, abdominal pain, flatulence, constipation, melaena, haematemesis, gastrointestinal Anticoagulants: NSAIDs may enhance the effects of anticoagulants, such as warfarin (see section 4.4).dose should be considered when potent CYP2C9 inhibitors are administered concomitantly, particularly when high-dose ibuprofen is administered with either voriconazole or fluconazole. The administration of an NSAID may cause a dose dependent reduction in prostaglandin formation and precipitate renal failure. The habitual concomitant intake of various similar painkillers further increases this risk. Patients at greatest risk of this reaction are those with impaired renal function, cardiac impairment, liver dysfunction, those taking diuretics and the elderly. For these patients, use the lowest effective dose, for the shortest possible duration and monitor renal function especially in long-term treated patients (see also section 4.3).

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty. Speak with a doctor before taking ibuprofen if you have ever had a bad reaction to any other anti-inflammatory painkiller.

Ibuprofen is also contraindicated in patients with a history of gastrointestinal bleeding or perforation, related to previous NSAID therapy. Ibuprofen should not be used in patients with active, or history of, recurrent peptic ulcer or gastrointestinal haemorrhage (two or more distinct episodes of proven ulceration or bleeding). If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work.

Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptoms (see section 4.4). For people who find it difficult to swallow tablets or capsules, ibuprofen is available as a tablet that melts in your mouth, granules that you mix with a glass of water to make a drink, and as a liquid.

Appropriate monitoring and advice are required for patients with a history of hypertension and/or mild to moderate congestive heart failure as fluid retention and oedema have been reported in association with NSAID therapy. Y Caution should be advised in patients receiving concomitant medications which could increase the risk of ulceration or bleeding, such as oral corticosteroids, anticoagulants such as warfarin, selective serotonin-reuptake inhibitors or antiplatelet agents such as aspirin (see section 4.5). Ibuprofen is best taken with food. This will help to protect your stomach from side-effects such as indigestion. If you have been prescribed a sachet containing ibuprofen granules (Brufen® Effervescent Granules), mix the contents of the sachet into a glass of water to make a fizzy drink. Drink it straightaway after mixing it.