Bergland Devil's Claw Cream 200 ml

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Devil’s claw is known by a variety of folk names, including grapple plant, wood spider and harpago. These creative monikers refer to the small “hooks” on the fruit of the plant. Diaz-Silveira GL, Deutsch J, Little DP. DNA Barcode Authentication of Devil's Claw Herbal Dietary Supplements. Plants (Basel). 2021 Sep 24;10(10):2005. doi:10.3390/plants10102005. Certain medications could potentially interact with devil’s claw, including medications changed by the liver, because devil’s claw may slow the liver’s breakdown of these substances. The clotting drug warfarin (brand names include Coumadin and Jantoven) may also be affected by devil’s claw. Versus Arthritis, the UK’s leading arthritis research charity, says ‘evidence suggests that devil’s claw may be as effective as conventional medicines for osteoarthritis. 10 Another way devil’s claw may help those with obesity is by potentially helping to prevent weight-related atherosclerosis (hardening of the arteries) by the particular way it suppresses inflammation. ( 13 ) 3. Natural Painkiller

Loew, D., Mollerfeld, J., Schrodter, A., Puttkammer, S., and Kaszkin, M. Investigations on the pharmacokinetic properties of Harpagophytum extracts and their effects on eicosanoid biosynthesis in vitro and ex vivo. Clin.Pharmacol.Ther. 2001;69(5):356-364. View abstract. Some products contain devil’s claw, but typical dosage used in studies consists of 750mg three times a day. Does devil’s claw really work?An extract of devil’s claw helped to suppress the formation of nitrites as the extract’s antioxidants acted in this lab test, suggesting to researchers that these extracts “may represent potential anti-inflammatory drugs in the treatment of glomerular inflammatory diseases.” ( 23 ) Munkombwe, N. M. Acetylated phenolic glycosides from Harpagophytum procumbens. Phytochemistry 2003;62(8):1231-1234. View abstract.

One of the reasons devil’s claw is so valuable is its ability to help reduce inflammation , which is at the root of most diseases. It’s possible devil’s claw may interact with certain medications. Consult your doctor before starting devil’s claw if you take other medications regularly. Moussard C, Alber D, Toubin MM, et al. A drug used in traditional medicine, harpagophytum procumbens: no evidence for NSAID-like effect on whole blood eicosanoid production in human. Prostaglandins Leukot Essent Fatty Acids. 1992;46:283-6.. View abstract. Gallstones: Devil's claw might increase bile production. This could be a problem for people with gallstones. Avoid using devil's claw.Ribbat JM and Schakau D. Behandluing chronisch aktivierter Schmerzen am Bewegungsapparat. NaturaMed 2001;16:23-30. For other conditions, sufficient studies to determine effective doses are unavailable. In addition, devil’s claw has only been used for up to one year in studies. However, devil’s claw appears to be safe for most people in doses up to 2,610 mg per day ( 29). This review reported five RCTs dating from 1980 into the use of devil’s claw for osteoarthritis of the hip or the knee. Chantre P, Cappelaere A, Leblan D, et al. Efficacy and tolerance or Harpagophytum procumbens versus diacerhein in treatment of osteoarthritis. Phytomedicine 2000;7:177-83. View abstract. When choosing a supplement, look for the concentration of harpagoside, an active compound in devil’s claw.

Bhattacharya A and Bhattacharya SK. Anti-oxidative activity of Harpagophytum procumbens. Br J Phytother 1998;72:68-71. Though test-tube and animal research indicates that devil’s claw can suppress inflammation, clinical studies to support its use for gout specifically are unavailable. Summary In addition to reducing pain, it’s possible that devil’s claw benefits arthritis sufferers by preventing bone loss. Although tests thus far have taken place only in lab and animal tests, there are promising results that suggest devil’s claw prohibits bone loss in inflammatory osteoporosis. ( 10 ) These results are conflicting when it comes to hormonally activated osteoarthritis. ( 11 ) 2. Might Aid in Weight Loss

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Soulimani R, Younos C, Mortier F, Derrieu C. The role of stomachal digestion on the pharmacological activity of plant extracts, using as an example extracts of Harpagophytum procumbens. Can J Physiol Pharmacol 1994;72:1532-6. View abstract. Due to its purported anti-inflammatory effects and potential to reduce pain, devil’s claw has been proposed as an alternative treatment for those with gout ( 20). Betancor-Fernandez, A., Perez-Galvez, A., Sies, H., and Stahl, W. Screening pharmaceutical preparations containing extracts of turmeric rhizome, artichoke leaf, devil's claw root and garlic or salmon oil for antioxidant capacity. J Pharm Pharmacol 2003;55(7):981-986. View abstract. Lanhers MC, Fleurentin J, Mortier F, et al. Anti-inflammatory and analgesic effects of an aqueous extract of Harpagophytum procumbens. Planta Med 1992;58:117-23 . View abstract.