Nurofen Period Pain Soft Capsules

Product Information

Hyperalgesia. Hyperalgesia Each ibuprofen tablet or capsule contains 200mg, 400mg or 600mg of ibuprofen. Slow-release tablets and capsules contain 200mg, 300mg or 800mg of ibuprofen. If you're taking alendronic acid it's best to avoid taking Nurofen unless it's been recommended by your doctor, because ibuprofen may increase the risk of irritation to the foodpipe, stomach or intestines. Cardiac glycosides: NSAIDs may exacerbate cardiac failure, reduce GFR and increase plasma glycoside levels.

Microcrystalline cellulose, Sodium starch glycollate, Hypromellose, Pregelatinised maize starch, Talc, Opaspray white colouring Use with concomitant NSAIDs, including cyclo-oxygenase-2 specific inhibitors - increased risk of adverse reactions. During treatment, you may be at risk of developing certain side effects. It is important you understand these risks and how to monitor for them. See additional information under Section 6. Are there any side effects? Pregnancy and breastfeeding Patients who have previously shown hypersensitivity reactions (e.g. asthma, rhinitis, angioedema, bronchospasm or urticaria) in response to ibuprofen, acetylsalicylic acid (aspirin) or other non-steroidal anti-inflammatory drugs (NSAIDs).Use of codeine containing products is contraindicated in women during breast feeding (see Section 4.6 Fertility, Pregnancy and Lactation, Use in lactation).

aged between 12 - 18 years in whom respiratory function might be compromised, including post tonsillectomy and/or adenoidectomy for obstructive sleep apnoea. Respiratory depression and death have occurred in some children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolisers of codeine due to a CYP2D6 polymorphism. Pain-relieving medication: Pain relievers that reduce the effects of prostaglandins are very effective for period pain. These pain relievers are called non-steroidal anti-inflammatory drugs (or NSAIDs for short) and include ibuprofen, the active ingredient in Nurofen Use of opioids in chronic (long-term) non-cancer pain (CNCP). Opioid analgesics have an established role in the treatment of acute pain, cancer pain and palliative and end-of-life care. Current evidence does not generally support opioid analgesics in improving pain and function for most patients with chronic non-cancer pain. The development of tolerance and physical dependence and risks of adverse effects, including hazardous and harmful use, increase with the length of time a patient takes an opioid. The use of opioids for long-term treatment of CNCP is not recommended. Ibuprofen is found alongside other active ingredients in many over-the-counter cold and flu remedies and non-prescription painkillers. In serious poisoning metabolic acidosis may occur and the prothrombin time/INR may be prolonged, probably due to interference with the actions of circulating clotting factors. Acute renal failure and liver damage may occur.

In patients aged between 12 - 18 years in whom respiratory function might be compromised, including post tonsillectomy and/or adenoidectomy for obstructive sleep apnoea, due to an increased risk of developing serious and life-threatening adverse reactions (see Section 4.4 Special Warnings and Precautions for Use, Paediatric use). Antihypertensives (ACE inhibitors and Angiotensin II Antagonists) and diuretics: since NSAIDs may diminish the effects of these drugs. In some patients with compromised renal function (e.g. dehydrated patients or elderly patients with compromised renal function) the co-administration of an ACE inhibitor or Angiotensin II antagonist and agents that inhibit cyclo-oxygenase may result in further deterioration of renal function, including possible acute renal failure, which is usually reversible. These interactions should be considered in patients taking a coxib concomitantly with ACE inhibitors or angiotensin II antagonists. Therefore, the combination should be administered with caution, especially in the elderly. Patients should be adequately hydrated and consideration should be given to monitoring of renal function after initiation of concomitant therapy, and periodically thereafter. Diuretics can increase the risk of nephrotoxicity of NSAIDs. Corticosteroids: as these may increase the risk of gastrointestinal ulceration or bleeding (see Section 4.4) When seeking medical attention, take this leaflet and remaining medicine with you to show the doctor. Also tell them about any other medicines or alcohol which have been taken. 5. What should I know while using Nurofen Plus? Things you should do Nurofen Joint & Muscular Pain Relief 200mg Medicated Plaster, For pain relief of muscular strains or sprains close to the joint of the upper or lower limb. Contain ibuprofen.

This medicine is only available with a doctor's prescription. What Nurofen Plus contains Active ingredient Patients with uncontrolled hypertension, congestive heart failure (NYHA II-III), established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease should only be treated with ibuprofen after careful consideration and high doses (2400 mg/day) should be avoided. More instructions can be found in Section 4. How do I use Nurofen Plus? in the full CMI. 5. What should I know while using Nurofen Plus? Things you should do

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You can become addicted to Nurofen Plus even if you take it exactly as prescribed. Nurofen Plus may become habit forming causing mental and physical dependence. If abused it may become less able to reduce pain. Dependence Nurofen Plus contains the active ingredients Ibuprofen and Codeine phosphate. Nurofen Plus is used to provide temporary relief of acute moderate pain and inflammation. For more information, see Section 1. Why am I using Nurofen Plus? in the full CMI. 2. What should I know before I use Nurofen Plus? If you’re taking granules, the usual dose for adults is one sachet 2 or 3 times a day. Some people might need to take it 4 times a day. When discontinuing Nurofen Plus in a person who may be physically-dependent, the drug should not be ceased abruptly but withdrawn by tapering the dose gradually (see Ceasing opioids; see Section 4.2 Dose and Method of Administration). Also see Section 4.4 Special Warnings and Precautions for Use, Paediatric use; Section 4.6 Fertility, Pregnancy and Lactation, Use in lactation.)

Anti-platelet agents and selective serotonin reuptake inhibitors (SSRIs): increased risk of gastrointestinal bleeding (see section 4.4).A white capsule-shaped tablet, containing ibuprofen 200 mg and codeine phosphate hemihydrate 12.8 mg. you are allergic to ibuprofen, codeine, other opioids, or any medicine containing ibuprofen, aspirin or other NSAIDs or any of the ingredients listed at the end of this leaflet. In children ingestion of more than 400mg/kg may cause symptoms. In adults the dose response effect is less clear cut. The half-life in overdose is 1.5-3 hours. People with an active peptic ulcer or bleeding in the gut; those who've had two or more episodes of this in the past; and people who have ever experienced bleeding or perforation in the gut as a result of taking an NSAID.