Gelomyrtol Forte 2x20 Capsules

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Increase of the mucociliary clearance: Due to the cited mucolytic, secretolytic and secretomotor effects, the natural cleaning mechanism of the mucous membranes is supported by ELOM-080. This means that mucus, inhaled particles and pathogens are increasingly evacuated (technically speaking: Mucociliary-Clearance-Enhancer, MCC-Enhancer). In one investigation on human cells of nasal mucous membranes, it was possible to demonstrate an increase of 46% in mucociliary clearance after addition of ELOM-080. [14] This effect may have prevented the formation of bacterial biofilms. It is suspected that such biofilms are capable of causing chronic nasal sinus inflammations. Biofilms protect the pathogenic bacteria from the body's own defence mechanisms and from antibiotics, thus forming a durable bacterial reservoir. [16] The effect of increased mucociliary clearance has been demonstrated experimentally and also repeatedly in human subjects. [12] [17] [18] [19] [20] [21] Ukoliko mislite da lek GeloMyrtol forte suviše slabo ili jako deluje na Vaš organizam, obratite se lekaru ili farmaceutu.

ELOM-080: Bei akuter Rhinosinusitis wirksam und gut verträglich". Der Hausarzt. Vol.4. mm medizin und medien Verlag GmbH. March 2019. p.63. ISSN 1434-8950 . Retrieved October 21, 2021. cineolo, limoneno ir α‑pineno didžiausia koncentracija kraujo plazmoje atsiranda maždaug po 1‑3 valandų po Gelomyrtol ir Gelomyrtol forte kapsulių pavartojimo. 1,8 cineolo AUC yra apie 20 kartų didesnė nei limoneno ir α‑pineno AUC. Pagridinių trijų medžiagų C max ir AUC tarp individų ir to paties individo organizme gali reikšmingai skirtis.Anti-inflammatory actions: Inflammations of the airways as in acute and chronic bronchitis, rhinosinusitis or in bronchial asthma are caused by various inflammatory cells and neurotransmitters ( inflammation mediators). In preclinical studies, ELOM-080 has led to reduced production of inflammation mediators in inflammatory cells. Among other effects, ELOM-080 inhibits 5-lipoxygenase, a key enzyme in the inflammation cascade, as well as formation of tumor necrosis factor alpha (TNFα). Beyond this, it has been possible to show that ELOM-080 inhibits the pro-inflammatory cytokines interleukin-6 and interleukin-8 as well as reduces the granulocyte-monocyte colony stimulating factor (GM-CSF). [21] [24] [25] In a mouse model for acute lung injury (ALI), ELOM-080 reduced LPS-induced lung injury, among other actions by inhibiting the neutrophil count, IL-6 and myeloperoxidase (MPO) activity. In addition, ELOM-080 inhibited the LPS-induced activation of the inflammation-promoting transcription factor NF-κB. [26] GeloMirtol 120 mg - one gastro-resistant capsule contains 120 mg standardised Myrtol, including at least 30 mg limonene (limonene), 30 mg cineole (cineole) and 8 mg .-pinene (pinene). Deci do 10 godina davati pola preporučene doze za odrasle osobe (gore pomenute). Za primenu kod dece konsultovati nadležnog pedijatra GeloMirtol forte 300 mg - one gastro-resistant capsule contains 300 mg Myrtol, standardised, including at least 75 mg limonene (limonene), 75 mg cineole (cineole) and 20 mg .-pinene (pinene). Secretomotor action (increased ciliary beat frequency): By virtue of their wavelike coordinated motions, the tiny hairs ( cilia) of the mucosal cells assist in clearance of mucus from the airways. The beat frequency of these cilia is accelerated by ELOM-080, thus shortening the mucus transit time. [12] [13] Thus, in one study, the ciliary beat frequency of mucous membrane samples was recorded with a microscope and a connected high-speed camera. The special distillate increased the ciliary beat frequency significantly in doses corresponding to the customary dosage in humans. In the process, the active ingredient tended to be more effective than N-acetylcysteine. [12] In further studies, it was possible to demonstrate an increase of 48% in the ciliary beat frequency. [14]

Prodaja ovog leka zabranjena je putem interneta zakonom Republike Srbije , dok je oglašavanje istog putem interneta dozvoljeno isključivo kao podsetnik i ima svrhu informisanja. Dėl veikliosios medžiagos tirpumo riebaluose, labai tikėtinas mažų koncentracijų patekimas į motinos pieną. Duomenų apie padidėjusį pavojų žindymo laikotarpiu vartojant Gelomyrtol/Gelomyrtol forte iki šiol gauta nebuvo. Kaip ir prieš vartojant kitokių vaistinių preparatų, žindymo laikotarpiu reikia pasitarti su gydytoju. ELOM-080 (previous designation Myrtol, registered trade mark [1]) is the active ingredient of the herbal medicine named GeloMyrtol forte. The acronym ELOM stands for the oils from Eucalyptus, Lemon, (Sweet) Orange and Myrtle that it contains. [2] Smeša etarskih ulja eukaliptusa (Eucalypti aetheroleum), slatke narandže (Aurantii dulcis), mirte (Myrti aetheroleum) i limuna (Limonis aetheroleum) (66:32:1:1), standardizovana na 1,8-cineol (75mg), d-limonen (75mg), i (+)-alfa-pinen (20mg) 300mg izraženo na supstancu. Secretolytic (mucus-liquefying) action: A mucus-liquefying effect has been observed in mice under administration of ELOM-080. In a direct comparison with untreated animals, the secretolytic action was increased by 32%. It was also increased by 21% during treatment with a pure eucalyptus oil preparation. [15] According to studies, this effect is to be attributed to increased chloride ion efflux, which leads to an osmotic gradient across the mucous membranes and in turn to passive water efflux. [14] The increased hydration of the mucus leads to its liquefaction.GeloMyrtol forte kapsule uzeti pola sata pre jela uz dosta hladne tečnosti. Za ugodan san, poslednja doza se uzima pre spavanja. Dužina terapije zavisi od simptoma. U slučaju hroničnih respiratornih bolesti, može se koristiti kao terapija održavanja. On the basis of the scientific literature, 4 professional medical societies recommend the use of ELOM-080 for treatment of sinusitis [16] [41] and coughing. [42] [43] Trade names [ edit ] Atidžiai perskaitykite visą šį lapelį, prieš pradėdami vartoti šį vaistą, nes jame pateikiama Jums svarbi informacija.

Sensitivity analysis will be used to identify the robustness of the review conclusions, such as methodological weaknesses, missing data, and heterogeneity qualities. 2.5.3 Evaluation of the quality of evidence Although there are many therapeutic measures to improve sinusitis, management is often challenging. Sinusitis is common in the general population, and it can affect the quality of life more than angina or respiratory disease. [7] Studies have shown that sinusitis causes 57% of patients to be absent from work, and 28% of patients to experience anxiety and depression. [8,9] Of the currently available sinusitis medications, the risks of using corticosteroids far exceed the benefits, [10] and the International Consensus Statement on Allergy and Rhinology (ICAR) guidelines note that there is insufficient evidence for antibiotic use. [11] Therefore, there is no consensus on the optimal management strategy. The special distillate contained in Gelo Myrtol 300 mg capsulesactivates the natural clearing of the airways. It liquefies viscous mucus and stimulates the glands to produce thin fluid secretion.

3. Kaip vartoti Gelomyrtol forte

Distillate of a mixture of rectified essential oils of eucalyptus, sweet orange, myrtle and lemon (66:32:1:1) Прочетете внимателно цялата листовка, преди да започнете да използвате това лекарство, тъй като тя съдържа важна за Вас информация. Kiekvienoje šio vaisto skrandyje neirioje minkštojoje kapsulėje yra ne daugiau kaip 50 mg sorbitolio. Ukolikoste uzeli veću dozu leka GeloMyrtol forte nego što bi trebalo, odmah razgovarajte sa Vašim lekarom ili farmaceutom! U retkim slučajevima može doći do gastrointestinalnih poremećaja i do pokretanja postojećih bubrežnih i žučnih kamenaca. Zabeleženi su retki slučajevi preosetljivosti (osip, otok lica, otežano disanje i poremećaj cirkulacije).