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The pharmacokinetics of nicotine has been extensively studied, and variations in delivery format have been found to have significant effects on rate and extent of absorption. Before use, please read the information leaflet carefully. Do not take more medicine than the label tells you to. Nicotine should be avoided during breast-feeding The relatively small amounts of nicotine found in breast milk during NRT use are less hazardous to the infant than second-hand smoke. Intermittent dose forms would minimize the amount of nicotine in breast milk and permit feeding when levels were at their lowest. Symptoms: Symptoms of overdose with nicotine from this product may occur in smokers/vapers who have previously had a low nicotine intake from cigarettes/e-cigarettes or if other sources of nicotine are used concomitantly with this product. Stopping smoking: Polycyclic aromatic hydrocarbons in tobacco smoke induce the metabolism of drugs metabolised by CYP 1A2 (and possibly by CYP 1A1). When a smoker stops smoking, this may result in slower metabolism and a consequent rise in blood levels of such drugs. This is of potential clinical importance for products with a narrow therapeutic window, e.g. theophylline, clozapine and ropinirole.
Nicotine metabolism and elimination are independent of the choice of nicotine formulation, and thus results from studies with intravenous administration of nicotine are used to describe biotransformation and elimination. Users should use one to two sprays when they would normally smoke a cigarette or have cravings to smoke.it gives me hiccups for about 5 minutes after spraying but this is NOT every time i use it. i think sometimes i must just spray wrong and trap air in my throat Transferred dependence: Transferred dependence is rare and is both less harmful and easier to break than smoking dependence. In males tobacco smoking reduces sperm production, increases oxidative stress, and DNA damage. Spermatozoa from smokers have reduced fertilizing capacity. Nicorette® contains nicotine. Stop smoking aid. Requires willpower. Always read the label. (12+ years) UK-NI-2300074
The adverse reactions observed in patients treated with oral nicotine formulations during clinical trials and post-marketing experience are listed below by System Organ Class (SOC).
About Nicorette
Although the frequency in the active group is less than that of the placebo group, the frequency in the specific formulation in which the PT was identified as a systemic ADR was greater in the active group than the placebo group.
Nicorette® are at the forefront of Nicotine Replacement Therapy (NRT) innovation, offering a range of products to suit your needs including, nicotine gum, nicotine patches, nicotine inhalators and nicotine chewing gum to help you to quit smoking.Quitting smoking cold turkey is not always the most effective method, with up to 76% of unaided quitters relapsing within the first week‡, so whether you want to cut down or stop smoking completely, Nicorette® will be there through each of the stages of quitting smoking. From preparing to quit smoking to during your journey to stop smoking, there is a Nicorette® product for you. In addition to this, other cessation-associated symptoms were seen in those using the mouth spray: dizziness, presyncopal symptoms, constipation, and gingival bleeding. Use of the nicotine by breast feeding smokers should only be initiated after advice from a health care professional. Women should take the product as soon as possible after breastfeeding. Use your thumb to slide down the button until you can push it lightly inwards. Don't push too hard. i would recommend this product to anyone trying to give up smoking and go for this instead of the vapes.
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