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In most cases, taking biotin won't hurt you. Experts say it's difficult to take so much biotin that you hurt yourself or overdose (Bistas, 2020). However, taking too much of it can have secondary health consequences, which we’ll discuss below. Once absorbed, sodium-dependent multivitamin transporter (SMVT) mediates biotin uptake into the liver. [4] SMVT also binds pantothenic acid, so high intakes of either of these vitamins can interfere with transport of the other. [19] Metabolism and excretion [ edit ]
György, P (December 1939). "The Curative Factor (vitamin H) for Egg White Injury, with Particular Reference to Its Presence in Different Foodstuffs and in Yeast". Journal of Biological Chemistry. 131 (2): 733–44. doi: 10.1016/S0021-9258(18)73468-6. Therefore, always let your doctor know of any supplements you take or plan to take that contain biotin. These may include some prenatal and multivitamins.a b c d e "Biotin". Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis, OR. October 21, 2015 . Retrieved January 16, 2018. The Dietary Supplement Health and Education Act of 1994 states that the US Food and Drug Administration must allow on the product label what are described as "Structure:Function" (S:F) health claims that ingredient(s) are essential for health. For example: Biotin helps maintain healthy skin, hair and nails. If a S:F claim is made, the label must include the disclaimer "This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease." [58] Animals [ edit ] Mushrooms have biotin, too. A 100-gram serving of portabella mushrooms (a little more than 1 cup) contains 11.1 micrograms. Biotin Deficiency a b Glynis, Ablon (November 2012). "A Double-blind, Placebo-controlled Study Evaluating the Efficacy of an Oral Supplement in Women with Self-perceived Thinning Hair". The Journal of Clinical and Aesthetic Dermatology. 5 (11): 28–34. PMC 3509882. PMID 23198010. Scientists are studying biotin to understand how it affects health. Here is an example of what this research has shown. Hair, nail, and skin health
Supports nervous system function – biotin works with other B vitamins to help maintain normal nervous system function. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Other Interactions Depending on the intended formulation and dosage form, Biotin supplements can be made through several processes. The most common method of producing biotin supplements is chemical synthesis. The biotin supplements can also be extracted from natural sources such as yeast, liver, and egg yolks. Still, these sources may not be as cost-effective or standardized as synthesized biotin.In addition to food, the bacteria in your intestines can make biotin. However, the role of gut bacteria on the overall biotin status of humans remains unknown — in part due to the complexity of the gut microbiota and the factors that influence its composition ( 8). Summary Processing nutrients from food –biotin supports the enzymes responsible for breaking down the fats, proteins and carbs from our food. Chen B, Wang C, Wang YM, Liu JX (July 2011). "Effect of biotin on milk performance of dairy cattle: a meta-analysis". J Dairy Sci. 94 (7): 3537–46. doi: 10.3168/jds.2010-3764. PMID 21700041. Great product! Very tasty and I look forward to them every morning. I feel so much more energised and my hair is shinier.” In 1916, W. G. Bateman observed that a diet high in raw egg whites caused toxic symptoms in dogs, cats, rabbits, and humans. [40] By 1927, scientists such as Margarete Boas and Helen Parsons had performed experiments demonstrating the symptoms associated with "egg-white injury." They had found that rats fed large amounts of egg-white as their only protein source exhibited neurological dysfunction, hair loss, dermatitis, and eventually, death. [41] [42]
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