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2PcsClearbreath Dendrobium & Mullein Extract - Powerful Lung Support & Cleanse & Respiratory,Clearbreath Dendrobium & Mullein Extract Herbal Drops,Dendrobium Mullein Extract for Lung

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Also, DF-A was shown to suppress EMT, as indicated by cadherin switch from N- to E-cadherin and decrease of Snail, Slug and vimentin, revealing thus the potential of DF-A as an anti-metastatic agent [ 44]. The ones, which are often explored, are cancer, neurodegenerative diseases and diabetes mellitus as they are widely associated to elderly. Both, DOP-1 and DOP-2 were evaluated with in vitro cell models and the data indicated that they exert significant immunomodulatory effects on innate immune responses mediated by spleen lymphocytes, natural-killer (NK) cells and macrophages. mg/mL after 3 weeks of reaction as against the same reaction time with vitamin C at the concentration of 0. Both are composed of mannose and glucose at similar ratios and have similar structure with a backbone of 1,4-linked β-D-mannopyranosyl and β-D-glucopyranosyl residues.

The sulfation occurred to C-2 and C-6 glucosyl residues seems also to be beneficial to enhance this activity [ 75]. The Chinese consider Dendrobium as one of the fifty fundamental herbs used to treat all kinds of ailments and use Dendrobium tonic for longevity.

Besides polysaccharides, phenolic compounds from Dendrobium aphyllum, namely moscatin, moscatilin and tricetin 3',4',5'-trimethyl ether 7- O-β-glucopyranoside, inhibited NO production at the concentration of 25 μM in LPS-stimulated RAW 264. In combination with ConA, both DCP-E and DCP-H could stimulate splenocyte proliferation of BALB/c mice with a dose-dependent relationship. cytotoxic, anti-proliferative, anti-metastatic, antitumor, anti-genotoxic, antimigratory or apoptotic properties in vitro or in vivo and suggest their potential anticancer effects. nobile (EDNLA) in LPS-induced hyperphosphorylation of tau protein in rat's hippocampus and LPS-induced apoptosis in rat brain. Western blotting analysis revealed that this compound greatly decreases epithelial to mesenchymal transition (EMT) markers, including N-cadherin, vimentin, and Slug, leading to a significant suppression of protein kinase B, extracellular signal-regulated kinase, and caveolin-1 survival pathways during the detached condition [ 39].

The active polysaccharide fraction of the mucilage was determined to have an average molecular weight of ~10kDa for the ratio of glucoside to mannoside (~1:10) and the degree of acetylation (~35%). Immunomodulatory effects of DTP administered orally to Balb/c mice for 3 weeks were investigated and it was concluded oral administration of 100 mg/kg and 300 mg/kg of DTP led to a 16. Among about 27,800 orchid species, Dendrobium represents one of the most important genera, ornamentally and medicinally. This effect appears to be due, at least in part, to suppression of LPS-induced overexpression of hippocampus tumor necrosis factor receptor 1 (TNFR1), possibly through inhibition of phosphorylated p38 mitogen activated protein kinases (p-p38 MAPK) and the downstream NF-κB signal pathway [ 16]. was to identify homogenous polysaccharide fractions with high intestinal immunomodulating activity from D.When taken by mouth: There isn't enough information to know if dendrobium is safe or what the side effects might be when taken by mouth. But at least one popular dendrobium-containing supplement (Craze, Driven Sports) has been identified by the U. investigated the effects and the possible mechanisms of the Dendrobium officinale extracts (DOE) on diabetic cardiomyopathy in streptozotocin (STZ)-induced mice (at the dose of 50 mg/kg b. denneanum were assessed for their neuroprotective activity against glutamate-induced toxicity in PC12 cells by an MTT assay.

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