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Physical diseases can be uncovered or ruled out by organic and hormonal examinations. In the case of such a disease, the mood swings usually disappear with the appropriate drug treatment. If there are psychological causes, the doctor can refer you to a psychotherapist. When to see a doctor for mood swings In the gastrointestinal tract, serotonin has a stimulating effect on the intestines, i.e. it influences intestinal movements (peristalsis) and thus also regulates bowel movements. In gastrointestinal problems, serotonin production increases, controlling diarrhea and nausea, among other things. For this it is advisable to approach the whole thing as a real, long-term dopamine fast or "dopamine detox". And if you're at risk of addiction, stay away from substances altogether that cause dopamine levels to rise rapidly.
The finished messenger substance dopamine is not contained in any food. Even if we could supply dopamine from outside through food, it would not be able to cross the blood-brain barrier. Therefore, it is first formed in the body, more precisely in the so-called dopaminergic nerve cells. However, certain "ingredients" are required for this. In this case, these are various nutrients: the amino acids tyrosineand phenylalanine, as well as vitamins B6, B12 and C. At the current time, the standard value for adults in urine concentrations is less than 620 µg/d; for blood plasma, it is reported as 50 picograms per milliliter. Each "happiness hormone" has specific tasks and effects. Some endorphins increase interest and desire for certain activities, they increase drive and provide a feeling of happiness (dopamine). Norepinephrine also increases motivation, activity and performance levels. Other endorphins increase the strength of bonding between people (oxytocin), while still other endorphins (such as serotonin) reduce anxiety, stress and aggression and make people feel balanced and content. Other functions of endorphins Endorphins not only increase well-being, but are also related to certain bodily functions, as shown by various studies. Endorphins and laughter That depends on the purpose for which the serotonin level is to be determined. Anyone who wants to know whether their serotonin level in the brain is high enough will not gain any insights into this with a blood test. This is because there is many times more serotonin in the digestive tract and lungs than in the brain, and the serotonin in the blood cannot cross the blood-brain barrier. Therefore, the concentration of serotonin in the blood has little significance for the serotonin content in the brain. The blood-brain barrier is also the reason why serotonin is produced not only in the intestine but also in the brain, where the neurotransmitter also performs important functions.Alternatively, the serotonin content in the body can be determined via urine. In everyday medical practice, it is common to use the collected urine from a 24-hour period for this purpose. However, it is not the serotonin itself that is measured, but a degradation product of the neurotransmitter, hydroxyindoleacetic acid (5-HIES for short). The amount of HIES measured in the urine allows indirect conclusions to be drawn about the serotonin level in the body. Dopamine-β-hydroxylase (DBH) is a neurotransmitter synthesizing enzyme that catalyzes the formation of norepinephrine from dopamine. Three vitamins are particularly important in the formation of dopamine: vitamin B6, vitamin B12 and vitamin C. A connection between happiness hormones and laughter is obvious. But it can also have a positive effect on the perception of pain. Researchers at Oxford University found this out when they put a blood pressure cuff on their test subjects and pumped it up until the subjects felt pain. The stimulus threshold for this pain was significantly higher in participants who had previously watched a funny video that made them laugh than in those who watched a neutral documentary. The scientists explain this result by the endorphins released by laughter, which reduce the sensation of pain. Endorphins and the placebo effect Exactly this often unconscious expectation of reward also plays an important role in addictions. Substances such as alcohol, cocaine or nicotine enhance the effect of dopamine and the associated consciously or unconsciously perceived feeling of happiness in the same way as certain behaviours are stimulated by the reward system.
Common Causes | What to do with mood swings When to the doctor | Tips for mild mood swings | Summary With treatment, most people with mental health problems can learn to manage their feelings and improve their quality of life. respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek Alternatively, it is possible to measure serotonin in urine. This is often done as part of a hospital stay, but is now possible at home with appropriate test kits. The tests make measuring serotonin in urine simple by sending a urine sample to a laboratory for professional evaluation. Bright light also seems to be able to stimulate serotonin production. Studies show that serotonin production and release in the brain changes depending on the season and time of day [4]. Daylight lamps, for example, which are used against the so-called winter blues and are supposed to stimulate serotonin production, are based on this effect. Conclusion on serotonin production
contributes to the protection of cells from oxidative stress (thanks to vitamin E, zinc and selenium) The second messenger substance known as the happiness hormone, dopamine, is also increasingly released by alcohol. Studies show that this connection is sometimes so close that even stimuli associated with alcohol can cause this increased dopamine release.As a result, increased cravings for alcohol and decreased control over alcohol consumption often occur[1]. This is because dopamine is part of the reward system in the brain. The release of the neurotransmitter is associated with many positive experiences such as the enjoyment of certain foods, sex, or even drugs such as alcohol, and acts as a reward. Therefore, it seems very desirable for the affected person and evokes the typical craving for alcohol, which unfortunately often ends in relapse [2]. Conclusion on alcohol and dopamine, serotonin and GABA
The dopamine level is determined in several ways, whereby such an examination is primarily carried out if a rare tumour of the adrenal gland is suspected. In this case, the doctor measures the concentration of dopamine, adrenaline and noradrenaline in the urine. Like the urine test, the blood test only has a certain significance if the values are elevated. We want the forums to be a useful resource for our users but it is important to remember that the forums are Serotonin wird aus der Aminosäure Tryptophan gebildet. Diese wandelt der Körper zunächst in die Aminosäure 5-HTP um. Als Zwischenprodukt hat sie keine eigene Funktion, sondern dient lediglich zur Herstellung von Serotonin. Die Umwandlung findet mithilfe spezieller Enzyme statt. Wie lang sie dauert, ist nicht bekannt. Vitamin B6 is involved in many metabolic processes. Among other things, it promotes the conversion of the dopamine precursor L-dopa into dopamine. In addition, B6 is important for a balanced mood, good sleep and the ability to concentrate. It is found primarily in whole grain products, but also in bananas and various vegetables such as cauliflower, green beans, potatoes and carrots. Dopamine exerts its effect via adrenoceptors or dopamine receptors. It increases motivation and drive and has a positive effect on a wide range of physical and mental functions. For example, dopamine has been shown to inhibit the release of prolactin and influence extrapyramidal motor function; the neuroanatomical physiological concept of our organism. This concept controls some of the motor abilities in humans.
This is mainly due to the fact that every person has a different dopamine value at which they feel well. Therefore, it has not yet been possible to standardize values for a proven deficiency. In addition, the measures before and during the measurement are very costly. The test kits contain everything you need to take the sample - including detailed instructions on the test procedure. You simply send the sample to the specified laboratory and receive the result after a few days. Conclusion about serotonin level measurement Both an underactive thyroid (hypothyroidism) and an overactive thyroid (hyperthyroidism) can affect mood. The hormones produced by the thyroid have a direct effect on metabolism and the brain and thus also influence the psyche and feelings . In Germany, 5 out of 100 people suffer from hypothyroidism [ 3 ] Mental mood swings
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